Marmaduke, a Great Dane, moves to California after his master, Phil, gets an offer to work at a dog-food company. Once there, Marmaduke makes friends very quickly at the dog park, and even becomes a bit of a celebrity after doing so well in a surfing competition. Unfortunately, it all goes to Marmaduke's head, and he shuns his new friends in favour of the limelight. But then disaster strikes, but will this help Marmaduke to understand the importance of friendship?