Rizwan Khan, an Indian Muslim who suffers from the Asperger syndrome, grew up in Mumbai but moves to San Francisco to live with family members when he reaches adulthood. He falls in love with Mandira and the two eventually marry. This initially happy tale takes a twist when the events of 9/11 take place and the general atmosphere sours in the USA. Following a tragedy, husband and wife separate but Rizwan, still in love, wants to win Mandira back but has to embark on a long journey across the United States to fulfil his dreams.
