Feeling that it's time for a change in her life, Dr. Kate Forester (Sandra Bullock) leaves the suburban Illinois locale where she completed her residency and takes a job at a busy Chicago hospital. One thing she is reluctant to leave behind is the uniquely beautiful house she has been renting - a spacious and artfully designed refuge with large windows that overlook a placid lake.On her way to the city, Kate leaves a note in the mailbox for lake house's next tenant, asking him to forward her mail and noting that the inexplicable painted paw prints he might notice by the front door where there when she moved in.But, when the next tenant arrives, he sees a much different picture. Alex Wyler (Keanu Reeves), a talented but frustrated architect working at a nearby construction site, finds the lake house badly neglected. And no sign of paw prints anywhere.Alex disregards Kate's note until, days later, while painting the weather-beaten jetty he sees a stray dog run across the fresh paint and then towards the entreance of the house, leaving paw prints exactly where Kate said they would be...